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Article

DNA analysis of Huntington's disease in southern Chinese.

Journal of medical genetics - 1 Feb 1995

Chan V, Yu Y L, Chan T P, Yip B, Chang C M, Wong M T, Chan Y W, Chan T K

Abstract excerpt

Allelic frequencies of RFLPs at loci closely linked to the HD gene, D4S95, D4S91, D4S141, and D4S90, were determined in 13 Huntington's disease (HD) patients from nine Chinese families and 129 normal subjects. These were similar for non-HD and HD chromosomes and the HD gene in Chinese is associated with multiple haplotypes. Hence the HD gene probably arose independently in the background haplotypes of the Chinese...

Topics

Alleles
Asian People
DNA
Genetic Markers
Genetics, Population
Haplotypes
Hemophilia A
Heterozygote
Humans
Huntington Disease
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repetitive Sequences, Nucleic Acid

beta-Thalassemia

Source

Open in PubMed Open full text

Identifiers

PMID: 7760321
DOI: 10.1136/jmg.32.2.120
PMCID: PMC1050233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7760321-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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