Article
Analysis of the (CAG)n repeat causing Huntington's disease in a Mexican population.
Clinical genetics - 1 Apr 1997
Alonso M E, Yescas P, Cisneros B, Martínez C, Silva G, Ochoa A, Montañez C
Abstract excerpt
We investigated the allele distribution of the polymorphic (CAG)n repeat in the IT15 gene in 96 normal subjects from the Mexican population and 83 unrelated patients with Huntington's disease. Our results show that the size distributions of normal and affected alleles do not overlap. Normal alleles range from 13 to 32 triplets, with 18 being the most frequent allele, while HD alleles contain 37 to 76 repeats with...
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