Article
Lack of allelic loss at the multiple endocrine neoplasia type 1 (MEN-1) gene locus in a pancreatic ductal (non-endocrine) adenocarcinoma of a patient with the MEN-1 syndrome.
Virchows Archiv : an international journal of pathology - 1 Jan 1995
Bordi C, Falchetti A, Azzoni C, D'Adda T, Morelli A, Peracchia A, Brandi M L
Abstract excerpt
The gene responsible for multiple endocrine neoplasia type I (MEN-1) syndrome has been mapped to chromosome 11q13. It appears to function as a tumour-suppressor gene analogous to that for retinoblastoma and allelic losses involving the wild-type of the MEN-1 allele have been found in parathyroid...
Topics
- Adenocarcinoma
- Aged
- Alleles
- Blotting, Southern
- Female
- Humans
- Liver Neoplasms
- Multiple Endocrine Neoplasia Type 1
- Pancreatic Neoplasms
- Polymerase Chain Reaction