Article
Human immunodeficiency virus type 1 (HIV-1) viremia changes and development of drug-related mutations in patients with symptomatic HIV-1 infection receiving alternating or simultaneous zidovudine and didanosine therapy.
The Journal of infectious diseases - 1 May 1995
Kojima E, Shirasaka T, Anderson B D, Chokekijchai S, Steinberg S M, Broder S, Yarchoan R, Mitsuya H
Abstract excerpt
The changes in viremia levels and the development of drug-related mutations were examined in 26 patients with symptomatic human immunodeficiency virus type 1 (HIV-1) infection participating in a randomized trial comparing alternating (A) and simultaneous (S) regimens of zidovudine and didanosine therapy. Patients on both arms had significant reduction in serum RNA copies from baseline throughout the 2 years of...
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