Article
Didanosine resistance in HIV-infected patients switched from zidovudine to didanosine monotherapy.
Annals of internal medicine - 15 Aug 1994
Kozal M J, Kroodsma K, Winters M A, Shafer R W, Efron B, Katzenstein D A, Merigan T C
Abstract excerpt
OBJECTIVE: To determine the frequency and pattern of development of specific drug resistance mutations for human immunodeficiency virus (HIV) reverse transcriptase in patients switched from zidovudine to didanosine therapy and to examine the relation of the didanosine resistance mutation at codon...
Topics
- CD4-Positive T-Lymphocytes
- Codon
- Didanosine
- Drug Resistance, Microbial
- Genes, Viral
- HIV
- HIV Infections
- Humans
- Leukocyte Count
- Mutation
- RNA, Viral
- RNA-Directed DNA Polymerase
- Retrospective Studies
- Zidovudine