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Article

[The multidrug resistance phenotype: some morphological and biological characteristics except efflux pump].

Bulletin du cancer - 1 May 1994

Jardillier J C, Colin M, Bobichon H, Akeli M G, Delvincourt C, Madoulet C

Abstract excerpt

Recent data from the literature together with personal results strongly suggest that multidrug resistance phenotype is overwhelming the sole expression of P170 glycoprotein efflux pump. Morphological alterations have been put in evidence in MDR cells after transmission and scanning electron microscopy. They include presence of osmiophilic vesicles and modifications of nuclear and nucleolar chromatin. Biological...

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PMID: 7749216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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