Article
[The multidrug resistance phenotype: some morphological and biological characteristics except efflux pump].
Bulletin du cancer - 1 May 1994
Jardillier J C, Colin M, Bobichon H, Akeli M G, Delvincourt C, Madoulet C
Abstract excerpt
Recent data from the literature together with personal results strongly suggest that multidrug resistance phenotype is overwhelming the sole expression of P170 glycoprotein efflux pump. Morphological alterations have been put in evidence in MDR cells after transmission and scanning electron micro...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Antineoplastic Agents
- Drug Carriers
- Drug Resistance, Multiple
- Gene Expression
- Humans
- Liposomes
- Lysosomes
- Models, Biological
- Neoplasm Metastasis
- Phenotype
- Tumor Cells, Cultured
- Vinblastine