Article
[Multidrug resistance of malignant tumors].
Orvosi hetilap - 6 Oct 1991
Bak M
Abstract excerpt
The development of resistance to chemotherapy is a major problem in the treatment of malignant tumors. Clinically, this is characterized by short periods of remission and failure to respond to subsequent therapy. Multidrug-resistance or pleiotropic resistance describes the simultaneous expression of cellular resistance to a vide range of structurally unrelated drugs (e.g. alkaloids, anthracyclines, antibiotics,...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Antibodies, Monoclonal
- Antineoplastic Combined Chemotherapy Protocols
- Drug Resistance
- Humans
- Immunohistochemistry
- Membrane Glycoproteins
- Neoplasm Proteins
- Neoplasms
- Phenotype
