Multidrug resistance: focus in hematology.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Multidrug resistance: focus in hematology.

Haematologica - 1 Jan 2000

Carulli G, Petrini M

Abstract excerpt

The appearance of chemoresistance is the most relevant limitation of chemotherapy. It has been shown that multidrug resistance (MDR) is frequently related to the expression of a membrane glycoprotein (P-170). This protein is able to bind ATP and leads to decreased accumulation of structurally unr...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
Antineoplastic Agents
Biological Transport, Active
DNA
Drug Resistance
Gene Expression Regulation, Neoplastic
Genes, Neoplasm
Killer Cells, Natural
Membrane Glycoproteins
Mice
Mutation
Neoplasm Proteins
Neoplasms
Neoplasms, Experimental
Phenotype
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 1980479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1980479-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics