Article
Prevalence of dementia and distribution of ApoE alleles in Japanese centenarians: an almost-complete survey in Yamanashi Prefecture, Japan.
Journal of the American Geriatrics Society - 1 Feb 1996
Asada T, Yamagata Z, Kinoshita T, Kinoshita A, Kariya T, Asaka A, Kakuma T
Abstract excerpt
OBJECTIVE: To determine the prevalence and types of dementia in centenarians and to examine whether the ApoE epsilon 4 allele has significant impact on the development of Alzheimer's disease (AD) in the population. DESIGN: Cross-sectional study and a 6-month prospective study. SETTING: Yamanashi...
Topics
- Age Distribution
- Aged
- Aged, 80 and over
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Case-Control Studies
- Cross-Sectional Studies
- Dementia
- Female
- Gene Frequency
- Geriatric Assessment
- Humans
- Japan
- Male
- Population Surveillance
- Prevalence
- Prospective Studies