Article
Prevalence of dementia and distribution of ApoE alleles in Japanese centenarians: an almost-complete survey in Yamanashi Prefecture, Japan.
Journal of the American Geriatrics Society - 1 Feb 1996
Asada T, Yamagata Z, Kinoshita T, Kinoshita A, Kariya T, Asaka A, Kakuma T
Abstract excerpt
OBJECTIVE: To determine the prevalence and types of dementia in centenarians and to examine whether the ApoE epsilon 4 allele has significant impact on the development of Alzheimer's disease (AD) in the population. DESIGN: Cross-sectional study and a 6-month prospective study. SETTING: Yamanashi Prefecture, Japan. PARTICIPANTS: Forty-seven centenarians participated in the study to determine the prevalence and...
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