Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease.

doi:10.1159/000026149

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Article

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease.

Neuroepidemiology - 1 Jan 1998

Notkola I L, Sulkava R, Pekkanen J, Erkinjuntti T, Ehnholm C, Kivinen P, Tuomilehto J, Nissinen A

Abstract excerpt

The epsilon 4 allele of the apolipoprotein E (apoE) is associated with Alzheimer's disease (AD) and also with elevated serum total cholesterol and low-density lipoprotein levels. However, the interrelationships between apoE genotype, plasma cholesterol levels and AD risk have been studied very li...

Topics

Adult
Age Factors
Aged
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Cholesterol
Female
Finland
Genotype
Humans
Longitudinal Studies
Male
Middle Aged
Psychiatric Status Rating Scales
Regression Analysis
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 9549720
DOI: 10.1159/000026149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9549720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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