Article
Two proximal CArG elements regulate SM alpha-actin promoter, a genetic marker of activated phenotype of mesangial cells.
The American journal of physiology - 1 Apr 1995
Simonson M S, Walsh K, Kumar C C, Bushel P, Herman W H
Abstract excerpt
Mesangial cells express smooth muscle alpha-actin (SM alpha-actin) in response to glomerular injury in vivo, and SM alpha-actin gene expression serves as a genetic marker characterizing the activated phenotype of mesangial cells. We used a molecular genetic approach to analyze the SM alpha-actin...
Topics
- Actins
- Animals
- Base Sequence
- Blood
- Endothelins
- Genes, Regulator
- Genetic Markers
- Glomerular Mesangium
- Male
- Molecular Sequence Data
- Muscle, Smooth
- Phenotype
