Article
Intronic CArG box regulates cysteine-rich protein 2 expression in the adult but not in developing vasculature.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2010
Chen Chung-Huang, Wu Meng-Ling, Lee Yi-Chung, Layne Matthew D, Yet Shaw-Fang
Abstract excerpt
OBJECTIVE: An absence of cysteine-rich protein 2 (CRP2) enhances vascular smooth muscle cell (VSMC) migration and increases neointima formation after arterial injury; therefore, CRP2 plays an important role in the response to vascular injury. The goal of the present study was to elucidate the molecular mechanisms that preserve CRP2 expression in the adult vasculature and thus might serve to inhibit the response...
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