Article
Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells.
American journal of physiology. Cell physiology - 1 Jan 2007
Kawai-Kowase Keiko, Owens Gary K
Abstract excerpt
Smooth muscle cell (SMC) differentiation is an essential component of vascular development and these cells perform biosynthetic, proliferative, and contractile roles in the vessel wall. SMCs are not terminally differentiated and possess the ability to modulate their phenotype in response to changing local environmental cues. The focus of this review is to provide an overview of the current state of knowledge of...
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