Article
Use of tissue culture and animal models to identify virulence-associated traits of Haemophilus ducreyi.
Infection and immunity - 1 May 1995
Alfa M J, Stevens M K, DeGagne P, Klesney-Tait J, Radolf J D, Hansen E J
Abstract excerpt
To identify virulence-associated properties of Haemophilus ducreyi, 34 strains of this sexually transmitted pathogen were evaluated for in vitro phenotypic characteristics of potential relevance to chancroid pathogenesis and for their ability to produce lesions in the temperature-dependent animal model for chancroid. Of the 34 strains tested, all but three produced a cytopathic effect on human foreskin...
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