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Article

Use of tissue culture and animal models to identify virulence-associated traits of Haemophilus ducreyi.

Infection and immunity - 1 May 1995

Alfa M J, Stevens M K, DeGagne P, Klesney-Tait J, Radolf J D, Hansen E J

Abstract excerpt

To identify virulence-associated properties of Haemophilus ducreyi, 34 strains of this sexually transmitted pathogen were evaluated for in vitro phenotypic characteristics of potential relevance to chancroid pathogenesis and for their ability to produce lesions in the temperature-dependent animal model for chancroid. Of the 34 strains tested, all but three produced a cytopathic effect on human foreskin...

Topics

Animals
Bacterial Adhesion
Cells, Cultured
Chancroid
Culture Techniques
Disease Models, Animal
Haemophilus ducreyi
Male
Phenotype
Rabbits
Skin

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Identifiers

PMID: 7729882
DOI: 10.1128/iai.63.5.1754-1761.1995
PMCID: PMC173220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7729882-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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