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Article

Evaluation of an isogenic hemolysin-deficient mutant in the human model of Haemophilus ducreyi infection.

The Journal of infectious diseases - 1 Jul 1998

Palmer K L, Thornton A C, Fortney K R, Hood A F, Munson R S, Spinola S M

Abstract excerpt

Haemophilus ducreyi causes the genital ulcerative disease chancroid. One putative virulence factor of H. ducreyi is a pore-forming hemolysin that displays toxicity against human fibroblasts and keratinocytes. In order to test the role of the hemolysin in pathogenesis, an isogenic hemolysin-deficient mutant was constructed, designated 35000HP-RSM1. The lipooligosaccharide, outer membrane protein patterns, and...

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Identifiers

PMID: 9652440
DOI: 10.1086/515617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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