Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>Haemophilusducreyi</i> Requires an Intact <i>flp</i> Gene Cluster for VirulenceinHumans

25 Nov 2003

Abstract excerpt

An intact Haemophilus ducreyi flp operon is essential for microcolony formation in vitro. tadA is the 9th of 15 genes in the operon and has homology to NTPases of type IV secretion systems. Fifteen human volunteers were experimentally infected with both H. ducreyi 35000HP and the tadA mutant, 35000HP.400. Papules developed at similar rates at sites inoculated with the mutant and parent, while pustules formed at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive tract infections research
Share to Syphilis Diagnosis and Treatment
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14638812
DOI: 10.1128/iai.71.12.7178-7182.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>Haemophilusducreyi</i> Requires an Intact <i>flp</i> Gene Cluster for VirulenceinHumansPMID 14638812Read ↗

Haemophilus ducreyi Requires the flp Gene Cluster for Microcolony Formation In VitroSemantic proximity Read ↗

Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers.Semantic proximity Read ↗

A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans.Semantic proximity Read ↗

A pilus-deficient mutant of Haemophilus ducreyi is virulent in the human model of experimental infection.Semantic proximity Read ↗

Haemophilus ducreyi SapA Contributes to Cathelicidin Resistance and Virulence in HumansSemantic proximity Read ↗

Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects.Semantic proximity Read ↗

A DltA mutant of Haemophilus ducreyi Is partially attenuated in its ability to cause pustules in human volunteers.Semantic proximity Read ↗

Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system.Semantic proximity Read ↗

DsrA-deficient mutant of Haemophilus ducreyi is impaired in its ability to infect human volunteers.Semantic proximity Read ↗

Infections caused by Haemophilus ducreyi: one organism, two storiesSemantic proximity Read ↗

Expression of peptidoglycan-associated lipoprotein is required for virulence in the human model of Haemophilus ducreyi infection.Semantic proximity Read ↗

Target Cell Range of <i>Haemophilus ducreyi</i> Hemolysin and Its Involvement in Invasion of Human Epithelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.