Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of (6-4)photoproduct formation with transforming mutations in UV-irradiated Ha-ras.

Carcinogenesis - 1 Apr 1995

Yagi T, Morimoto T, Takebe H

Abstract excerpt

Sites and types of mutations in relation to the amount of cyclobutane pyrimidine dimers (CPDs) and (6-4)-photoproducts in UV-irradiated normal Ha-ras sequences were investigated. Mouse BALB/C 3T3 cells were transfected with UV-irradiated pYN-mHras plasmids containing mouse normal Ha-ras sequences, and transformed foci developed. Direct DNA sequencing of the Ha-ras retrieved from the foci revealed that most...

Topics

3T3 Cells
Animals
Base Sequence
DNA
DNA Damage
Genes, ras
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
Photochemistry
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pyrimidine Dimers

Transfection

Transformation, Genetic

Ultraviolet Rays

Source

Identifiers

PMID: 7728944
DOI: 10.1093/carcin/16.4.689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7728944-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of (6-4)photoproduct formation with transforming mutations in UV-irradiated Ha-ras.PMID 7728944Read ↗

Mutations induced by ultraviolet light.Semantic proximity Read ↗

Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells.Semantic proximity Read ↗

Involvement of 5-methylcytosine in sunlight-induced mutagenesis.Semantic proximity Read ↗

8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene: effects of sequence contexts on mutation spectra.Semantic proximity Read ↗

c-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjacent positions.Semantic proximity Read ↗

An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions.Semantic proximity Read ↗

Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight.Semantic proximity Read ↗

UV-induced DNA damage in carcinogenesis and its repair.Semantic proximity Read ↗

The consequence of translesional replication of unique UV-induced photoproducts.Semantic proximity Read ↗

Effect of sequence context on Polζ-dependent error-prone extension past (6-4) photoproducts.Semantic proximity Read ↗

N-ras mutation in ultraviolet radiation-induced murine skin cancers.Semantic proximity Read ↗

Mutations induced by DNA lesions in hot spots of the c-Ha-ras gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.