Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UV-induced DNA damage in carcinogenesis and its repair.

Journal of dermatological science - 1 Mar 2000

Nishigori C

Abstract excerpt

The purpose of this study is to ask what kind of DNA damage is involved in UV carcinogenesis. Firstly, ras gene alterations were analyzed in UV-induced mice skin cancers. Five types of base changes resulting in activated ras were detected in nine UV-induced skin cancers. Unexpectedly, transversions predominated, whereas previous findings using shuttle vectors indicated that UVC predominantly causes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to Genes, p53
Share to Genes, ras

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Damage

Share to Neoplasms, Radiation-Induced

Share to Skin Neoplasms

Share to Ultraviolet Rays

Share to Xeroderma Pigmentosum

Source

Identifiers

PMID: 10764991
DOI: 10.1016/s0923-1811(99)00079-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UV-induced DNA damage in carcinogenesis and its repair.PMID 10764991Read ↗

Role of reactive oxygen species in skin carcinogenesis.Semantic proximity Read ↗

Role of UVA in the pathogenesis of melanoma and non‐melanoma skin cancer: A short reviewSemantic proximity Read ↗

Mechanisms of UV-induced mutations and skin cancerSemantic proximity Read ↗

Mutations induced by ultraviolet light.Semantic proximity Read ↗

In Vivo Spectrum of UVC-induced Mutation in Mouse Skin Epidermis May Reflect the Cytosine Deamination Propensity of Cyclobutane Pyrimidine Dimers.Semantic proximity Read ↗

Cellular aspects of photocarcinogenesis.Semantic proximity Read ↗

UVA1 genotoxicity is mediated not by oxidative damage but by cyclobutane pyrimidine dimers in normal mouse skin.Semantic proximity Read ↗

The mechanisms of UV mutagenesis.Semantic proximity Read ↗

TP53 mutations in human skin cancers.Semantic proximity Read ↗

High mutation frequency in ras genes of skin tumors isolated from DNA repair deficient xeroderma pigmentosum patients.Semantic proximity Read ↗

P53 and the Ultraviolet Radiation-Induced Skin Response: Finding the Light in the Darkness of Triggered CarcinogenesisSemantic proximity Read ↗

Ultraviolet radiation-induced carcinogenesis: Mechanisms and experimental modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.