UV-induced DNA damage in carcinogenesis and its repair.

doi:10.1016/s0923-1811(99)00079-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

UV-induced DNA damage in carcinogenesis and its repair.

Journal of dermatological science - 1 Mar 2000

Nishigori C

Abstract excerpt

The purpose of this study is to ask what kind of DNA damage is involved in UV carcinogenesis. Firstly, ras gene alterations were analyzed in UV-induced mice skin cancers. Five types of base changes resulting in activated ras were detected in nine UV-induced skin cancers. Unexpectedly, transversions predominated, whereas previous findings using shuttle vectors indicated that UVC predominantly causes...

Topics

Animals
DNA Damage
DNA Repair
Genes, p53
Genes, ras
Humans
Mice
Mutation
Neoplasms, Radiation-Induced
Skin Neoplasms
Ultraviolet Rays
Xeroderma Pigmentosum

Source

Open in PubMed

Identifiers

PMID: 10764991
DOI: 10.1016/s0923-1811(99)00079-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics