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Article

Alpha 2 adrenergic receptor subtypes in depression: a candidate gene study.

Journal of affective disorders - 1 Jul 1992

Wang Z, Crowe R R, Tanna V L, Winokur G

Abstract excerpt

Alpha 2 adrenergic receptors play an important role in regulating the neuronal release of norepinephrine through presynaptic feedback inhibition in the locus ceruleus. Therefore, alpha 2 adrenergic autoreceptors may underlie some aspects of the pathogenesis and symptomatic expression of depressive illness. We studied two brain-expressed alpha 2 adrenergic receptor genes as genetic markers in linkage analyses in...

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Identifiers

PMID: 1326569
DOI: 10.1016/0165-0327(92)90005-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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