A systematic search for a bipolar predisposing locus on chromosome 5.

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Article

A systematic search for a bipolar predisposing locus on chromosome 5.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 1992

Detera-Wadleigh S D, Berrettini W H, Goldin L R, Martinez M, Hsieh W T, Hoehe M R, Encio I J, Coffman D, Rollins D Y, Muniec D

Abstract excerpt

Chromosome 5 markers spanning the pter to the qter were used to examine linkage to bipolar illness in 14 pedigrees. Twenty-four loci were examined in 237 individuals, of whom 69 were either bipolars or schizoaffectives. Marker genotypes were determined for each individual and lod scores were calc...

Topics

Bipolar Disorder
Chromosomes, Human, Pair 5
Family
Female
Genetic Linkage
Genetic Markers
Genome
Genotype
Humans
Male
Nucleic Acid Hybridization

Source

Open in PubMed

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PMID: 1632891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1632891-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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