Article
Genetic differences between BCG substrains.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Feb 1995
Zhang Y, Wallace R J, Mazurek G H
Abstract excerpt
SETTING: University-affiliated Mycobacteriology Reference Laboratory. OBJECTIVE: To determine the genetic differences of 25 BCG isolates representing 16 referenced substrains. DESIGN: Non-randomized, observational study based on the visual comparison of the large restriction fragment (LRF) patter...
Topics
- DNA Restriction Enzymes
- DNA, Bacterial
- Electrophoresis, Gel, Pulsed-Field
- Genetic Variation
- Mycobacterium bovis
- Polymorphism, Restriction Fragment Length
