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Bacillus Calmette–Guérin strain differences as the basis for immunotherapies against bladder cancer

5 Mar 2018

Abstract excerpt

In the past 40 years, intravesical immunotherapy with Mycobacterium bovis bacillus Calmette-Guérin has been carried out as the most effective treatment for preventing local recurrences and tumor progression of non-muscle-invasive bladder cancer. Bacillus Calmette-Guérin is a family of vaccines derived in 1921 by the in vitro attenuation of Mycobacterium bovis. Subsequently, bacillus Calmette-Guérin seed lots were...

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PMID: 29506322
DOI: 10.1111/iju.13538

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