Article
BCG--different strains, different vaccines?
The Lancet. Infectious diseases - 1 Feb 2002
Behr Marcel A
Abstract excerpt
After nearly a century of use, BCG vaccines continue to generate controversy and confusion. Their ability to prevent tuberculosis in studies has been inconsistent. When they have been protective, no clear mechanism of action has been established. Furthermore, the existence of different BCG strains has been described since the 1940s. These strains vary according to several laboratory properties, which may or may...
Topics
- BCG Vaccine
- Gene Deletion
- History, 20th Century
- History, 21st Century
- Humans
- Mutation
- Mycobacterium tuberculosis
- Polymorphism, Genetic
- Species Specificity
- Tuberculosis
