Familial meningioma is not allelic to neurofibromatosis 2.

doi:10.1212/wnl.43.10.2096

Back to search

Article

Familial meningioma is not allelic to neurofibromatosis 2.

Neurology - 1 Oct 1993

Pulst S M, Rouleau G A, Marineau C, Fain P, Sieb J P

Abstract excerpt

Meningiomas frequently lose parts of chromosome 22 (CHR 22), suggesting that a meningioma tumor-suppressor gene is located on CHR 22. Since meningiomas are common in neurofibromatosis 2 (NF2) and the NF2 gene is mapped to CHR 22, the NF2 gene is a candidate for the meningioma gene. To determine w...

Topics

Alleles
Base Sequence
Chromosome Aberrations
Chromosomes, Human, Pair 22
DNA Primers
DNA Probes
DNA, Satellite
Female
Genetic Linkage
Genetic Markers
Humans
Male
Meningeal Neoplasms
Meningioma
Molecular Sequence Data
Neurofibromatosis 2
Pedigree
Software

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.