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[MECHANISMS OF ATTENUATION OF COLD-ADAPTED STRAIN A/KRASNO- DAR/101/35/59 (H2N2)].

Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000

Markushin S G, Svitich O A, Kinkulkina A R, Koptyaeva I B, Lisovskaya K V

Abstract excerpt

AIM: Study of mechanisms of attenuation of cold-adapted (ca) influenza virus strain A/ Krasnodar/101/35/59 (H2N2), associated with disruption of NS1 protein functions. MATERIALS AND METHODS: Study of interferonogenic activity of ca strain A/Krasnodar/101/35/59 (H2N2), its parent variant A/Krasnodar/101/59 (H2N2), virulent strain A/WSN/33 (H1N1) and a number of single gene and multiple gene reassortants between...

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PMID: 27228671

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