[The effect of mutation in the NS gene on the biological properties of the influenza virus].

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Article

[The effect of mutation in the NS gene on the biological properties of the influenza virus].

Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000

Dubrovina T Ia, Egorov A Iu, Ivanova I A, Pokhil'ko A V, Poliak R Ia

Abstract excerpt

The biological properties of influenza virus strain A/PR/8/34, virulent from mice, and its variant 25A-1, obtained by hybridization with avirulent strain A/Leningrad. This reassortant 25A-1 included 7 genes of its virulent parent strain and only gene NS of the avirulent one, which contained a sin...

Topics

Animals
Cells, Cultured
Chick Embryo
Genes, Viral
Influenza A virus
Lung
Mice
Mice, Inbred CBA
Mutation
Phenotype
Reassortant Viruses
Time Factors
Viral Nonstructural Proteins
Virulence
Virus Cultivation
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 7660707

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7660707-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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