Article
[The effect of mutation in the NS gene on the biological properties of the influenza virus].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Dubrovina T Ia, Egorov A Iu, Ivanova I A, Pokhil'ko A V, Poliak R Ia
Abstract excerpt
The biological properties of influenza virus strain A/PR/8/34, virulent from mice, and its variant 25A-1, obtained by hybridization with avirulent strain A/Leningrad. This reassortant 25A-1 included 7 genes of its virulent parent strain and only gene NS of the avirulent one, which contained a single mutation in position 798 (ATG=>ATA), inducing amino acid change MET=>IIe in position 100 of the polypeptide chain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
