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Article

Mutation of p53 in squamous cell cancer of the head and neck: relationship to tumor cell proliferation.

The Laryngoscope - 1 Jun 1997

Wood N B, Kotelnikov V, Caldarelli D D, Hutchinson J, Panje W R, Hegde P, Leurgans S, LaFollette S, Taylor S G, Preisler H D, Coon J S

Abstract excerpt

Rapid proliferation of squamous cell carcinomas of the head and neck (SCCHN) during therapy may contribute to treatment failure. We have investigated the presence of p53 abnormalities in patients with SCCHN as a correlate of proliferation rate and other pathologic and clinical variables. p53 Mutation, as determined by polymerase chain reaction and single-strand conformation polymorphism analysis of microdissected...

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Source

Identifiers

PMID: 9185741
DOI: 10.1097/00005537-199706000-00019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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