Article
Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese.
Human immunology - 1 Mar 1994
Onuma H, Ota M, Sugenoya A, Inoko H
Abstract excerpt
To investigate the association between HLA antigens and Graves' disease among Japanese, serologic typing and DPB1 genotyping using the PCR-RFLP method have been performed. HLA alleles of 106 patients with Graves' disease were determined, and the frequency of HLA-B46 was found to be significantly increased. Furthermore, the frequencies of HLA antigens were compared between two age groups: early-onset and...
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