Article
Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese.
Human immunology - 1 Mar 1994
Onuma H, Ota M, Sugenoya A, Inoko H
Abstract excerpt
To investigate the association between HLA antigens and Graves' disease among Japanese, serologic typing and DPB1 genotyping using the PCR-RFLP method have been performed. HLA alleles of 106 patients with Graves' disease were determined, and the frequency of HLA-B46 was found to be significantly...
Topics
- Adolescent
- Adult
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- Graves Disease
- HLA Antigens
- HLA-DP Antigens
- HLA-DP beta-Chains
- Humans
- Japan
- Male
- Middle Aged
