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Article

Swelling-activated chloride channels in multidrug-sensitive and -resistant cells.

The Journal of general physiology - 1 Dec 1994

Ehring G R, Osipchuk Y V, Cahalan M D

Abstract excerpt

Resistance to chemotherapeutic agents in neoplastic cells is often mediated by expression of P-glycoprotein, which functions as a drug-efflux pump for a broad range of substrates. We have used a combination of patch clamp and video-imaging techniques to examine the expression and drug-efflux function of P-glycoprotein and to determine the possible correlation with swelling-activated chloride channels in...

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Identifiers

PMID: 7699367
DOI: 10.1085/jgp.104.6.1129
PMCID: PMC2229248

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NPPB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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