Article
Yeast artificial chromosome and radiation hybrid map of loci in chromosome band 8p22, a common region of allelic loss in multiple human cancers.
Genomics - 15 Nov 1994
Bookstein R, Levy A, MacGrogan D, Lewis T B, Weissenbach J, O'Connell P, Leach R J
Abstract excerpt
Polymorphic alleles at loci such as LPL (lipoprotein lipase) and MSR (macrophage scavenger receptor) in chromosome band 8p22 are frequently lost during the genesis of several types of human cancer, including colorectal, non-small cell lung, hepatocellular, and prostatic carcinomas. A physical map...
Topics
- Alleles
- Base Sequence
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Chromosome Deletion
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 8
- Colorectal Neoplasms
- DNA Primers
- Genes, Tumor Suppressor
- Humans
- Hybrid Cells
- Lipoprotein Lipase
- Liver Neoplasms
- Lung Neoplasms
- Male
- Molecular Sequence Data
- Neoplasms