Article
Chromosome region 8p11-p21: Refined mapping and molecular alterations in breast cancer
1 Jul 1998
Abstract excerpt
Several genes, most of them unknown, of the short arm of chromosome 8 are involved in malignant diseases. Numerous studies have implicated a portion of the 8p11-p21 region as the location of one or more tumor suppressor genes involved in a variety of human cancers, including breast cancer. We and others have reported linkage analyses suggesting the presence of a putative breast cancer susceptibility gene....
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