Article
Distribution of Ha-ras alleles in patients with colorectal cancer and Crohn's disease.
Gut - 1 Dec 1991
Klingel R, Mittelstaedt P, Dippold W G, Meyer zum Büschenfelde K H
Abstract excerpt
The allele distribution of the Ha-ras gene on chromosome 11p was analysed by the restriction fragment length polymorphism of the enzymes Mspl/Hpall in 238 individuals. The investigation covered 116 patients with colorectal carcinoma and 122 patients with Crohn's disease, representing two patient populations with the same ethnic origin, one with a malignant and the other a benign disease of the same organ system....
Topics
- Alleles
- Blotting, Southern
- Colorectal Neoplasms
- Crohn Disease
- Disease Susceptibility
- Genes, ras
- Genotype
- Humans
- Polymorphism, Restriction Fragment Length