Article
Genetic susceptibility associated with rare HRAS1 variable number of tandem repeats alleles in Spanish non-small cell lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 1999
Rosell R, Calvo R, Sánchez J J, Maurel J, Guillot M, Monzó M, Núñez L, Barnadas A
Abstract excerpt
The highly polymorphic HRAS1 variable number of tandem repeats (VNTR), which maps 1 kb downstream from the human H-ras1 gene, has been described as an inherited predisposing factor in many human cancers. Here, we investigated the association between the presence of rare HRAS1 minisatellite alleles and lung cancer in the population studied. Four hundred sixty-six HRAS1 VNTR alleles from 233 lung cancer patients...
Topics
- Alleles
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Case-Control Studies
- DNA, Neoplasm
- Female
- Genes, ras
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Lung Neoplasms
- Lymphocytes
- Male