Article
Allelic differences affecting invariant chain dependency of MHC class II subunit assembly.
Immunity - 1 Mar 1995
Bikoff E K, Germain R N, Robertson E J
Abstract excerpt
The conserved invariant chain associates with highly polymorphic alpha and beta subunits guiding class II transport through the secretory pathway. Early associations of these three polypeptides inside antigen-presenting cells are poorly understood. The present experiments provide a detailed pictu...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Base Sequence
- Histocompatibility Antigens Class II
- Interleukin-4
- Lipopolysaccharides
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Sequence Data
- Precipitin Tests
- Protein Conformation
