Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epstein-Barr virus recombinants with specifically mutated BCRF1 genes.

Journal of virology - 1 Dec 1993

Swaminathan S, Hesselton R, Sullivan J, Kieff E

Abstract excerpt

Epstein-Barr virus (EBV) recombinants with specifically mutated BCRF1 genes were constructed and compared with wild-type BCRF1 recombinants derived in parallel for the ability to initiate and maintain latent infection and growth transformation in primary human B lymphocytes. A stop codon insertion after codon 116 of the 170-codon BCRF1 open reading frame or deletion of the entire gene had no effect on latent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Gene Deletion
Share to Genes, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Recombination, Genetic

Share to RNA, Viral

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7693971
DOI: 10.1128/JVI.67.12.7406-7413.1993
PMCID: PMC238205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epstein-Barr virus recombinants with specifically mutated BCRF1 genes.PMID 7693971Read ↗

The Epstein–Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformationSemantic proximity Read ↗

Cloning of the Epstein-Barr virus-related rhesus lymphocryptovirus as a bacterial artificial chromosome: a loss-of-function mutation of the rhBARF1 immune evasion gene.Semantic proximity Read ↗

The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential.Semantic proximity Read ↗

A comprehensive library of mutations of Epstein Barr virus.Semantic proximity Read ↗

Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: Effects on EBV transcription and lytic replication.Semantic proximity Read ↗

Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production.Semantic proximity Read ↗

An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation.Semantic proximity Read ↗

Epstein-Barr virus recombinant molecular genetic analysis of the LMP1 amino-terminal cytoplasmic domain reveals a probable structural role, with no component essential for primary B-lymphocyte growth transformation.Semantic proximity Read ↗

The Epstein-Barr Virus BILF1 Gene Encodes a G Protein-Coupled Receptor That Inhibits Phosphorylation of RNA-Dependent Protein KinaseSemantic proximity Read ↗

A selectable marker allows investigation of a nontransforming Epstein-Barr virus mutant.Semantic proximity Read ↗

Epstein-Barr virus (EBV) recombinants: use of positive selection markers to rescue mutants in EBV-negative B-lymphoma cells.Semantic proximity Read ↗

Early Events Associated with Infection of Epstein-Barr Virus Infection of Primary B-CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.