A selectable marker allows investigation of a nontransforming Epstein-Barr virus mutant.

doi:10.1128/JVI.66.5.3214-3219.1992

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Article

A selectable marker allows investigation of a nontransforming Epstein-Barr virus mutant.

Journal of virology - 1 May 1992

Marchini A, Cohen J I, Wang F, Kieff E

Abstract excerpt

The derivation of specifically mutated Epstein-Barr virus (EBV) recombinants is dependent on strategies to identify, enumerate, and clone infected B lymphocytes. In recent experiments, EBV recombinants containing a positive selection marker were identified and cloned in B-lymphoma (BL) cells infe...

Topics

Cell Transformation, Viral
Genetic Markers
Herpesvirus 4, Human
Humans
Lymphoma, B-Cell
Mutation
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Tumor Cells, Cultured

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