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Article

An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation.

Journal of virology - 1 Dec 1999

Kaye K M, Izumi K M, Li H, Johannsen E, Davidson D, Longnecker R, Kieff E

Abstract excerpt

An Epstein-Barr virus (EBV) recombinant (MS231) that expresses the first 231 amino acids (aa) of LMP1 and is truncated 155 aa before the carboxyl terminus transformed resting B lymphocytes into lymphoblastoid cell lines (LCLs) only when the infected cells were grown on fibroblast feeder cells (K. M. Kaye et al., J. Virol. 69:675-683, 1995). Higher-titer MS231 virus has now been compared to wild-type (WT) EBV...

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Identifiers

PMID: 10559372
DOI: 10.1128/JVI.73.12.10525-10530.1999
PMCID: PMC113109

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An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation.PMID 10559372Read ↗

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