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Early Events Associated with Infection of Epstein-Barr Virus Infection of Primary B-Cells

25 Sept 2009

Abstract excerpt

Epstein Barr virus (EBV) is closely associated with the development of a vast number of human cancers. To develop a system for monitoring early cellular and viral events associated with EBV infection a self-recombining BAC containing 172-kb of the Epstein Barr virus genome BAC-EBV designated as MD1 BAC (Chen et al., 2005, J.Virology) was used to introduce an expression cassette of green fluorescent protein (GFP)...

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PMID: 19784370
DOI: 10.1371/journal.pone.0007214

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