Article
Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production.
Journal of virology - 1 Dec 2017
Masud H M Abdullah Al, Watanabe Takahiro, Yoshida Masahiro, Sato Yoshitaka, Goshima Fumi, Kimura Hiroshi, Murata Takayuki
Abstract excerpt
Epstein-Barr virus (EBV), a member of human gammaherpesvirus, infects mainly B cells. EBV has two alternative life cycles, latent and lytic, and is reactivated occasionally from the latent stage to the lytic cycle. To combat EBV-associated disorders, understanding the molecular mechanisms of the EBV lytic replication cycle is also important. Here, we focused on an EBV lytic gene, BKRF4. Using our anti-BKRF4...
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