Article
The role of T cells in primary biliary cirrhosis.
Seminars in liver disease - 1 May 1997
Van de Water J, Shimoda S, Niho Y, Coppel R, Ansari A, Gershwin M E
Abstract excerpt
While fervently studied by several laboratories, the role of T cells in the pathogenesis of primary biliary cirrhosis (PBC) still remains a mystery. The studies concerning cell phenotype, antigen specificity, and major histocompatibility complex (MHC)-T-cell receptor (TCR) interaction gathered thus far all address important aspects of this intriguing conundrum. However, the lack of an animal model and the genetic...
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