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Article

T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes.

Autoimmunity - 1 Jan 1993

Voskuhl R R, Martin R, Bergman C, Dalal M, Ruddle N H, McFarland H F

Abstract excerpt

Multiple sclerosis (MS) is widely accepted as an autoimmune disease with myelin basic protein (MBP) a candidate autoantigen. In the current report, human T cell lines specific for an immunodominant region of MBP were shown to have a functional phenotype similar to T helper 1 (Th1) inflammatory cells of the mouse on the basis of their antigen-specific cytotoxic activity and production of interferon-gamma and...

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Source

Identifiers

PMID: 7692995
DOI: 10.3109/08916939309043888

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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