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Article

CD1-dependent regulation of chronic central nervous system inflammation in experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2004

Teige Anna, Teige Ingrid, Lavasani Shahram, Bockermann Robert, Mondoc Emma, Holmdahl Rikard, Issazadeh-Navikas Shohreh

Abstract excerpt

The existence of T cells restricted for the MHC I-like molecule CD1 is well established, but the function of these cells is still obscure; one implication is that CD1-dependent T cells regulate autoimmunity. In this study, we investigate their role in experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis, using CD1-deficient mice on a C57BL/6 background. We show that CD1-/- mice...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14688325
DOI: 10.4049/jimmunol.172.1.186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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