Article
Cellular characteristics of Chinese hamster cell mutants resembling ataxia telangiectasia cells.
Mutation research - 1 Oct 1993
Jongmans W, Verhaegh G W, Sankaranarayanan K, Lohman P H, Zdzienicka M Z
Abstract excerpt
The radiosensitive Chinese hamster V79 cell mutants (V-C4, V-E5 and V-G8), isolated previously in our laboratory, have been shown to resemble human ataxia telangiectasia (A-T) cells. These hamster cell mutants were further characterized with respect to cross-sensitivity to different radiomimetic...
Topics
- Aminoglycosides
- Animals
- Anti-Bacterial Agents
- Ataxia Telangiectasia
- Cell Line
- Cell Survival
- Cricetinae
- Doxorubicin
- Enediynes
- Etoposide
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Mutagens
- Mutation
- Streptonigrin