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Article

Bridge-building between mathematical theory and molecular biology: the REV2 gene as paradigm.

Mutation research - 1 Sept 1993

Eckardt-Schupp F, Ahne F

Abstract excerpt

The DNA damage-repair theory of R.H. Haynes anticipated the possibility of dose-dependent repair processes. The mathematical formalism developed by Haynes and coworkers on the basis of this theory provided tools to probe for the existence of inducible components of mutation or recombination by analysis of dose-response curves. Subsequently, we found that biological and molecular analysis of the Saccharomyces...

Topics

Amino Acid Sequence
Base Sequence
DNA Damage
DNA Repair
Genes, rev
Mathematics
Models, Theoretical
Molecular Biology
Molecular Sequence Data
Mutation
Sequence Homology, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7689161
DOI: 10.1016/0027-5107(93)90128-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7689161-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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