Article
The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control.
Mutation research - 29 Dec 2002
Murakumo Yoshiki
Abstract excerpt
Translesion DNA synthesis (TLS) is an important damage tolerance system which rescues cells from severe injuries caused by DNA damage. Specialized low fidelity DNA polymerases in this system synthesize DNA past lesions on the template DNA strand, that replicative DNA polymerases are usually unable to pass through. However, in compensation for cell survival, most polymerases in this system are potentially...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
