Contribution of direct and indirect recognition pathways to T cell alloreactivity.

doi:10.1084/jem.177.6.1643

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Article

Contribution of direct and indirect recognition pathways to T cell alloreactivity.

The Journal of experimental medicine - 1 Jun 1993

Liu Z, Sun Y K, Xi Y P, Maffei A, Reed E, Harris P, Suciu-Foca N

Abstract excerpt

T cells from an HLA-DR11/DR12 responder were stimulated in mixed lymphocyte culture with cells carrying the DR1 antigen. After priming, T cells proliferated in response to both DR1-positive-stimulating cells and a peptide derived from a polymorphic region of the HLA-DR beta 1*0101 chain presented...

Topics

Alleles
Clone Cells
Epitopes
Graft Rejection
HLA-DR Antigens
Humans
Immunization
Receptors, Antigen, T-Cell, alpha-beta
T-Lymphocytes

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