Article
Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells.
1 Apr 1996
Abstract excerpt
The role of endothelial cells (EC) in initiating a primary T cell response is of importance in clinical transplantation and autoimmunity since EC are the first allogeneic target encountered by the recipient's immune system and may display tissue-specific autoantigens in the context of an inflammatory response. In this study, we have investigated the antigen-presenting cell function of human umbilical vein-derived...
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