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Pathways of Antigen Recognition by T Cells in Allograft Rejection

10 Nov 2022

Abstract excerpt

The adaptive immune response leading to the rejection of allogeneic transplants is initiated and orchestrated by recipient T cells recognizing donor antigens. T-cell allorecognition is mediated via 3 distinct mechanisms: the direct pathway in which T cells recognize allogeneic major histocompatibility complex (MHC) molecules on donor cells, the indirect pathway through which T cells interact with donor peptides...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 36398330
DOI: 10.1097/tp.0000000000004420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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