Article
Molecular analysis of viable spontaneous and radiation-induced albino (c)-locus mutations in the mouse.
Mutation research - 1 Apr 1993
Rinchik E M, Stoye J P, Frankel W N, Coffin J, Kwon B S, Russell L B
Abstract excerpt
Thirty-one homozygous-viable, radiation-induced or spontaneous mutations at the albino (c) locus in mouse chromosome 7 were analyzed by Southern blot analysis with a tyrosine cDNA clone and with probes derived from the closely linked proviral integration sites Pmv-31 and Emv-23, which flank the t...
Topics
- Albinism
- Animals
- Blotting, Southern
- Chromosomes
- Cloning, Molecular
- DNA Mutational Analysis
- DNA Probes
- Gamma Rays
- Genetic Linkage
- Leukemia Virus, Murine
- Mice
- Mice, Inbred C3H
- Monophenol Monooxygenase
- Mutation
- Restriction Mapping
- Sequence Deletion
- Virus Integration