Article
Mosaicism of tyrosinase-locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygous chinchilla-mottled mice.
Developmental genetics - 1 Jan 1991
Porter S, Larue L, Mintz B
Abstract excerpt
The chinchilla-mottled (cm) mutation at the mouse tyrosinase-encoding locus leads to a transversely striped pattern of dark- and light-grey coat colors in homozygotes. The same basic pattern occurs in various other genotypes and has previously been found to represent the clonal developmental hist...
Topics
- Alleles
- Animals
- Chromatin
- Clone Cells
- Color
- Deoxyribonuclease I
- Gene Rearrangement
- Genes
- Homozygote
- Melanocytes
- Mice
- Monophenol Monooxygenase
- Mosaicism
- Pigments, Biological
- Promoter Regions, Genetic
- Transcription, Genetic